Evaluation of Antibacterial Activity of Selected Edible Herbs Against Genital Mycoplasmas Among University Students in Enugu State, Nigeria

نویسندگان

چکیده

The prevalence rates of Mycoplasma hominis and Ureaplasma Spp the evaluation edible herbs against genital mycoplasmas were determined among university students in Enugu state, Nigeria. Specimens from 2400 subjects comprising 1200 male female tested for Mycoplasma hominis Ureaplasma Spp. Cultures done on agar, A7agar urea-arginine LYO2 broth. Antimicrobial susceptibility pattern was by IST2 kit. Preliminary qualitative phytochemical analysis using standard methods to reveal presence basic phytochemicals. Rizomes Curcuma longa, garlic ginger, cloves seeds Garcina kola extracted with water, methanol ethanol sequentially reconstituted dimethyl -sulfoxide concentrations (mg/ml) 200, 100, 50, 25, 12.5, 6.25, 3.125 1.56. isolates screened sensitivity extracts agar well diffusion broth methods. occurred more women at (81.6%) while men (88%). (98%) (91.6%) showed high sensitivityto ciprofloxacin. The test plants all alkaloids, tannis, flavonoids, terpenoids, saponins, phenols cardiac glycosides. At 200mg/ml Curcurma longa higher zones inhibition 35mm ureaplasma Syngestic activities ethanolic Curcuma longa 45mm spp. minimum inhibitory concentration (MIC) results syngestic 1.56mg/ml isolates. Results study that there is area. synergistic selected efficacy resistant suggest its use treatment Mycoplasmas.

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ژورنال

عنوان ژورنال: American Journal of Biomedical and Life Sciences

سال: 2022

ISSN: ['2330-8818', '2330-880X']

DOI: https://doi.org/10.11648/j.ajbls.20221002.14